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1.
Ann Saudi Med ; 44(2): 67-72, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38615188

RESUMO

BACKGROUND: Inevitably, the floors of mosques are contaminated with microorganisms, and the risk of pathogen transmission is probably high between the many visitors, but the issue has been infrequently studied. OBJECTIVES: Investigate microorganism variety and risk of contamination on commonly used carpets and rosaries (prayer beads). DESIGN: Cross-sectional. SETTINGS: Mosques. METHODS: This study was carried out in three different cities of Turkey in 2023, focusing on mosques located around hospitals. Forty mosques were included in the study and from each mosque 10 samples were collected from various parts of carpets and rosaries. The number of positive culture isolates were identified. MAIN OUTCOME MEASURES: Diversity and distribution of microorganisms isolated from mosque carpets and rosaries; methicillin-resistance rates in Staphylococci. SAMPLE SIZE: 400 samples. RESULTS: Growth was observed in 368 (92%) of 400 samples examined. The microorganisms isolated in the highest number were methicillin-susceptible coagulase negative Staphylococci (MSCoNS) (59.8%), Microcooccus (41%) and diphtheroids (31.3%). The rates of total growth (P=.001), including diphtheroids (P=.018), methicillin-resistant coagulase negative Staphylococci (P=.001), Bacillus spp. (P=.036) and Aspergillus spp. (P=.002) rates were significantly higher in the rosary samples than carpet samples. At mosques in Tokat, a province center, 4 samples were positive for Acinetobacter baumannii, two samples were positive for Pseudomonas aeruginosa and one sample for methicillin-resistant Staphylococcus aureus (MRSA), and these were isolated from rosaries. 0.3% of Staphylococcus isolates were MRSA. CONCLUSION: As there is a high risk of contamination of carpets and prayer beads on the mosque floor with human flora, the use of appropriate hygiene practices is necessary. We also found some emerging bacteria in addition to the normal human flora. LIMITATIONS: Our study was conducted in three provinces. Further studies might cover a wider geography.


Assuntos
Coagulase , Staphylococcus aureus Resistente à Meticilina , Humanos , Estudos Transversais , Pisos e Cobertura de Pisos , Meticilina
2.
J Hazard Mater ; 470: 134278, 2024 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-38631247

RESUMO

Resuspension caused by human walking activities is an important source of indoor bioaerosols and has been associated with health effects such as allergies and asthma. However, it is unknown whether inhalation of resuspended bioaerosols is an important exposure pathway for airborne infection. Also, crucial factors influencing the resuspension of settled microbes have not been quantified. In this study, we experimentally investigated the resuspension of culturable bacteria from human-stepping on polyvinyl chloride (PVC) flooring under different conditions. We determined the bacterial resuspension emission factor (ER), a normalized resuspension parameter for the ratio of resuspended mass in the air to the mass of settled particles, for two common bacteria, Escherichia coli and Salmonella enterica. The investigation involved varying factors such as microbial surface-attached durations (0, 1, 2, and 3 days), the absence or presence of nutrients on flooring surfaces, and changes in relative humidity (RH) (35%, 65%, and 85%). The results showed that, in the absence of nutrients, the highest ER values for E. coli and S. enterica were 3.8 × 10-5 ± 5.2 × 10-6 and 5.3 × 10-5 ± 6.0 × 10-6, respectively, associated with surface-attached duration of 0 days. As the surface-attached duration increased from 0 to 3 days, ER values decreased by 92% and 84% for E. coli and S. enterica, respectively. In addition, we observed that ER values decreased with the increasing RH, which is consistent with particle adhesion theory. This research offers valuable insights into microbial resuspension during human walking activities and holds the potential for assisting in the assessment and estimation of risks related to human exposure to bioaerosols.


Assuntos
Escherichia coli , Umidade , Caminhada , Humanos , Pisos e Cobertura de Pisos , Salmonella enterica , Aerossóis , Poluição do Ar em Ambientes Fechados , Microbiologia do Ar , Cloreto de Polivinila/química , Nutrientes
3.
Sci Total Environ ; 924: 171459, 2024 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-38438041

RESUMO

The increasing application of nanotechnology has resulted in a growing number of nano-enabled consumer products, and they could be important contributors to indoor particulate matter, with potential adverse health effects. This study investigated the exposure of adults and children to the released and resuspended manufactured particles from seven nano-enabled consumer sprays. Sedimentation and resuspension of released particles were investigated in a newly constructed 2.8 × 1.6 × 2.4 m3 chamber. The resuspension of deposited particles was investigated as a function of product type, flooring material (e.g., carpet and vinyl), resuspension force (e.g., walking by an adult and motion of a robotic sampler that simulated a child), and measurement height. The concentration of released and resuspended particles in the air was determined using Button Aerosol Samplers (SKC Inc.) with 25-mm 2 µm-pore PTFE filters. Samplers were positioned in the experimenter's breathing zone (e.g., 1.5 m for adults and 0.3 m for a child-simulating robot) and at fixed stations of 0.3 m and 1.1 m heights. Resuspended particle mass concentrations ranged from 28 to 905 µg/m3, and the resuspension rates of deposited spray particles for the same variable combinations varied from 10-4 to 10-1 h-1, depending on product type, flooring material, sampling height, and resuspension force. Particle resuspension rates from carpet were up to 320 % higher than resuspension rates from vinyl flooring, resuspension rates measured at 0.3 m were up to 195 % higher than the rates measured with a 1.1 m stationary sampler, and resuspension rates due to a walking adult were up to 243 % higher than resuspension rates caused to a moving robot that simulated a child. Overall, these data on the resuspension of particles from nano-enabled consumer sprays could help us understand the resulting exposures and support future studies on human exposure reduction.


Assuntos
Poluição do Ar em Ambientes Fechados , Humanos , Tamanho da Partícula , Poluição do Ar em Ambientes Fechados/análise , Material Particulado , Aerossóis/análise , Pisos e Cobertura de Pisos
4.
Vet J ; 304: 106098, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38462169

RESUMO

Corkscrew claw (CC) in dairy cattle is increasingly reported in dairy herds. CC is a progressive deformity of the claw capsule with uncertain aetiology and pathogenesis. Genetics and specific environmental factors are suspected of contributing to the development of this irreversible condition. CC has been found in lame cows; however, the cause and effect has not been established. To perform analysis of risk factors, treatment and pathogenesis, a definition of severity scores is called for. The aim of this study was to measure and analyse CC characteristics from photos of cows' feet to describe and evaluate a scoring system for CC. Width of the visible part of the axial wall, degree of contact between the toe and the floor and angle of the distal part of the abaxial wall as a proxy for the deviation of the abaxial wall was measured from 393 pictures of CC. Based on the measurements on the claws, the parameter "width of the axial wall" was chosen to define the scores. The parameter was divided into three intervals to define either mild CC 0.3-2.0 cm, moderate CC 2.1-3.5 cm or severe CC>3.5 cm and correlation between the parameters; level of contact between the toe and the floor and the angle of the distal abaxial wall was evaluated. There was a significant positive linear correlation between width of the axial wall and angle of the distal part of the abaxial wall (r=0.91), the wider the axial wall, the more the abaxial wall deviated in the distal part. As the width of the axial wall increased the toe increasingly lost contact with the floor, this association was significant for mild CC and moderate CC but not for severe CC. The Interobserver agreement of the CC Scoring system was tested by 30 claw trimmers each scoring 32 cadaver feet and by 2 trained observers on 28 photos of feet using Cohen´s weighted kappa and showed substantial to almost perfect agreement between untrained and trained observers, respectively.


Assuntos
Doenças dos Bovinos , Doenças do Pé , Casco e Garras , Feminino , Bovinos , Animais , Casco e Garras/patologia , Doenças do Pé/veterinária , Doenças do Pé/patologia , Pé/patologia , Pisos e Cobertura de Pisos , Doenças dos Bovinos/patologia , Coxeadura Animal/etiologia
5.
Appl Ergon ; 117: 104249, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38368655

RESUMO

Slippery surfaces due to oil spills pose a significant risk in various environments, including industrial workplaces, kitchens, garages, and outdoor areas. These situations can lead to accidents and falls, resulting in injuries that range from minor bruises to severe fractures or head trauma. To mitigate such risks, the use of slip resistant footwear plays a crucial role. In this study, we aimed to develop an Artificial Intelligence model capable of classifying footwear as having either high or low slip resistance based on the geometric characteristics and material parameters of their outsoles. Our model was trained on a unique dataset comprising images of 37 indoor work footwear outsoles made of rubber. To evaluate the slip resistant property of the footwear, all samples were tested using a cart-type friction measurement device, and the static and dynamic Coefficient of Frictions (COFs) of each outsole was determined on a glycerol-contaminated surface. Machine learning techniques were implemented, and a classification model was developed to determine high and low slip resistant footwear. Among the various models evaluated, the Support Vector Classifier (SVC) obtained the best results. This model achieved an accuracy of 0.68 ± 0.15 and an F1-score of 0.68 ± 0.20. Our results indicate that the proposed model effectively yet modestly identified outsoles with high and low slip resistance. This model is the first step in developing a model that footwear manufacturers can utilize to enhance product quality and reduce slip and fall incidents.


Assuntos
Inteligência Artificial , Glicerol , Humanos , Projetos Piloto , Sapatos , Desenho de Equipamento , Fricção , Aprendizado de Máquina , Pisos e Cobertura de Pisos
6.
Poult Sci ; 103(4): 103542, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38417331

RESUMO

The type of litter material has direct impacts on production, behavioral, and welfare parameters of broilers. The price of conventionally-used litter materials is increasing. Salvinia molesta is a fast-growing aquatic plant which has become an environmental issue in some areas. This study assessed the suitability of air-dried Salvinia plants (SAL) as an alternate litter material to paddy husk (PH). Resulting in a completely randomized experiment, a total of 240 broilers was raised in 12 floor-pens each provided with either PH or SAL as litter materials, from 11 to 36 d. Scan sampling technique was employed to record the birds' engagement in 15 predetermined behaviors. Foot pad dermatitis (FPD), hock burn damage (HBD) and plumage cleanliness (PC) were assessed using Welfare Quality Scoring System. Litter samples were analyzed for pH, dry matter%, water holding capacity, porosity, N%, tapped-density and ammonia emission rate. The litter material had no significant effect (P > 0.05) on mortality, growth performance parameters, dressing % and visceral organ weight. The scores for FPD and PC were unaffected by the litter materials. SAL litter reported significantly lower (P < 0.05) HBD scores. The percentages of birds engaged in eating and wing flapping behaviors were significantly lower on SAL. Litter type had no significant influence on the color, aroma, flavor, texture and overall acceptability of breast meat. Air-dried Salvinia plants reported acidic pH. SAL litter gave a significantly higher tapped-density. Ammonia emission rate of SAL litter was significantly lower than that of PH. However, the final litter N content was higher for PH (3.7%) than SAL (3.2%). The study proposes air-dried Salvinia plants as a litter material for broilers since it gives growth performance comparable to PH with reduced hock burn damage incidences. Effects of SAL on behavior and the fertilizer value of the spent litter are to be studied further.


Assuntos
Doenças do Pé , Doenças das Aves Domésticas , Animais , Doenças do Pé/veterinária , Amônia/química , Galinhas , Abrigo para Animais , Doenças das Aves Domésticas/epidemiologia , Esterco , Pisos e Cobertura de Pisos
7.
PLoS One ; 19(1): e0296786, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38241210

RESUMO

Adolescents and youth living with HIV (AYLHIV) experience worse health outcomes compared to adults. We aimed to understand the experiences of AYLHIV in care in the youth-focused Red-Carpet program in Kenya to assess the quality of service provision and identify programmatic areas for optimization. We conducted focus group discussions among 39 AYLHIV (15-24 years) and structured analysis into four thematic areas. Within the HIV testing theme, participants cited fear of positive results, confidentiality and stigma concerns, and suggested engaging the community and youth in HIV testing opportunities. Within the HIV treatment adherence theme, participants cited forgetfulness, stigma, adverse side effects, lack of family support, and treatment illiteracy as barriers to adherence. Most participants reported positive experiences with healthcare providers and peer support. In terms of the HIV status disclosure theme, AYLHIV cited concerns about their future capacity to conceive children and start families and discussed challenges with understanding HIV health implications and sharing their status with friends and partners. Youth voices informing service implementation are essential in strengthening our capacity to optimize the support for AYLHIV within the community, at schools and healthcare facilities.


Assuntos
Pisos e Cobertura de Pisos , Infecções por HIV , Adulto , Criança , Humanos , Adolescente , Quênia , Infecções por HIV/diagnóstico , Infecções por HIV/tratamento farmacológico , Grupos Focais , Estigma Social , Teste de HIV
8.
Commun Biol ; 7(1): 141, 2024 01 31.
Artigo em Inglês | MEDLINE | ID: mdl-38297065

RESUMO

To enhance the practice of farmed-coral transplantation, we conducted a trial of an approach called "Reef Carpets" (RC), which draws inspiration from the commercial turf-grass sod in land-based lawn gardening. Three 8.4m2 RCs were established on a sandy seabed, containing preselected combinations of branching corals (Acropora cf. variabilis, Pocillopora damicornis, Stylophora pistillata) with nursery recruited dwellers, and were monitored for 17-months. Corals within RCs grew, supported coral recruitment and offered ecological habitats for coral-associated organisms. While the unstable sediment underneath the RCs increased corals' partial mortalities, corals managed to grow and propagate. The extent of fish and gastropods corallivory varied among the coral species and planulation of Stylophora transplants was significantly higher than same-size natal-colonies. The RCs provided conducive environments for fish/invertebrate communities (183 taxa), and each coral species influenced specifically species-diversity and reef-associated communities. Even dead corals played crucial roles as habitats for reef biota, sustaining >80% of the RCs diversity; hence, they should not be considered automatically as indicators of failure. RCs scaled-up reef restoration and generated, in short periods, new reefs in denuded zones with enhanced biodiversity. Yet, RCs employment on soft-beds could be improved by using more structured artificial frameworks, requiring further research efforts.


Assuntos
Antozoários , Animais , Recifes de Corais , Sobrevivência , Pisos e Cobertura de Pisos , Biodiversidade , Peixes
9.
Environ Res ; 245: 118064, 2024 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-38160965

RESUMO

Volatile organic compounds (VOCs) significantly affect the air quality in aircraft cabins, consequently affecting passenger health and comfort. Although VOC emission sources and their contributions have been studied extensively, the distribution characteristics of VOCs originating from diverse sources within cabins have received limited attention, and the correlation between VOC sources and concentrations in passenger breathing zones remains largely unexplored. To fill this knowledge gap, the concentration field of VOCs was investigated using a computational fluid dynamics model, and the results were experimentally validated in a typical single-aisle aircraft cabin with seven seat rows. The diffusion characteristics of different VOCs emitted by four typical sources in aircraft cabins (floors, human surfaces, seats, and respiratory sources) were analyzed and compared. The distribution of VOCs emitted by different sources was nonuniform and could be classified into two distinct categories. When the emission intensities of all sources were equal, the average concentration of VOCs emitted from the floor source were considerably lower in the passenger breathing zone (4.01 µg/m³) than those emitted from the human surface, seat, and respiratory sources, which exhibited approximately equal concentrations (6.82, 6.90, and 7.29 µg/m³, respectively). The analysis highlighted that the simplified lumped-parameter method could not accurately estimate the exposure concentrations within an aircraft cabin. To address this issue, we propose a correction method based on the emission intensity of each VOC source. This study provides critical insights into the diffusion characteristics of VOCs within aircraft cabins and VOC emissions from various sources.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Compostos Orgânicos Voláteis , Humanos , Compostos Orgânicos Voláteis/análise , Poluição do Ar/análise , Aeronaves , Pisos e Cobertura de Pisos , Hidrodinâmica , Poluentes Atmosféricos/análise , Monitoramento Ambiental
10.
Gait Posture ; 107: 42-48, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37734190

RESUMO

BACKGROUND: Reducing fall-related injuries is difficult due to the multi-factorial nature of falls, and challenges in implementing injury-preventative strategies. While safety floors are effective at absorbing energy and reducing fall-related impact forces, the low stiffness component of these floors may impair an individual's balance and mobility, thereby increasing fall risk. RESEARCH QUESTION: Therefore, the objective of this study was to investigate the influence of compliant flooring (i.e., safety flooring) on balance and mobility in young and older adults. METHODS: Kinematics were measured with inertial measurement units from 20 young and 10 older adults. Static balance was evaluated during quiet stance on three flooring surfaces (traditional, safety, foam) with three stance positions (regular, tandem, one-legged). Mobility was evaluated using the 3 m timed-up-and-go test on two flooring surfaces (traditional, safety). RESULTS: All participants were able to complete quiet standing trials on normal and safety flooring surfaces; however, most older adults could not complete one-legged stance trials or standing on foam. Significant age-related effects were observed for several balance and mobility tasks, particularly during the more challenging tandem stance condition, and the dynamic timed-up-and-go mobility test. In contrast, the introduction of safety flooring (compared to traditional flooring) had limited effects on balance/mobility (1 of 16 outcome variables showed negative effects). SIGNIFICANCE: Overall, the findings demonstrate minimal effects of a novel safety floor compared to the age-related differences, and provide insights to assist researchers, consumers, and industry stakeholders in the development of environments that support safe movement and maintained independence for older adults.


Assuntos
Pisos e Cobertura de Pisos , Equilíbrio Postural , Humanos , Idoso , Estudos de Tempo e Movimento , Movimento
11.
Appl Ergon ; 114: 104110, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37595332

RESUMO

Shoe outsole design strongly influences slip and fall risk. Certain tread features that can be readily measured have been shown to predict friction performance. This research aimed to replicate those findings and quantify their ability to predict slipping. Participants (n = 34) were exposed to a low friction oil-coated floor surface, while wearing slip-resistant shoes. The coefficient of friction (COF) of each shoe were predicted based on tread surface area, the presence of a bevel, and hardness. The COF was measured, and the slip outcome was determined. Predicted and measured COF were correlated, and measured COF was a sensitive predictor of slip outcome. The relationship of predicted COF on slip outcome was weaker than anticipated and was not statistically significant. This study partially confirmed the ability of previous regression equations to predict COF. However, the effect size was weaker than previously reported and predicted COF was not sensitive for predicting slips.


Assuntos
Pisos e Cobertura de Pisos , Sapatos , Humanos , Fricção , Estudos Prospectivos
12.
Poult Sci ; 103(2): 103322, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38100940

RESUMO

Producers are moving toward cage-free systems to house laying hens. These include aviary styles with multilevel wire enclosures and litter areas on the floor. In aviaries with doors hens can be confined within the tiered enclosure, which can be done to promote oviposition in nests and prevent hens from laying eggs in litter. However, there are multiple genetic strains of laying hen used in the egg industry, and some show different temporal patterns for key behaviors that could affect when they want to be on litter. For example, though dust bathing by laying hens is typically considered to peak in early afternoon, there may be variation in timing of motivation to dust bathe among strains. Differences in hens' temporal patterns, coupled with aviary configurations or management practices, may restricts birds' ability to perform important behaviors, such as dust bathing (DB), when they would most prefer to do them. Our objective was to determine if there were strain differences in the temporal pattern of DB. We examined the timing of DB in 4 strains of laying hen (Hy-Line Brown [HB], Bovans Brown [BB], DeKalb White [DW], and Hy-Line W36 [W36]) housed in aviaries using 144 hens of each strain per aviary unit (4 units/strain). We recorded the number of hens DB and on litter using instantaneous scan sampling every 5 min using video collected at 26 and 28 wk of age beginning at 11:35 (when litter access began each day) to 20:00 (lights off). Brown strains acclimated to litter access more slowly than white strains. Hens of all strains DB most often soon after gaining access to litter, and more white hens (DW and W36) DB simultaneously and in the presence of more conspecifics. Further examination of diurnal rhythm of behaviors, such as dust bathing, under unconstrained conditions by a range of genetic strains of laying hens is needed to design management practices and aviary styles that best meet hens' needs.


Assuntos
Galinhas , Poeira , Animais , Feminino , Galinhas/genética , Abrigo para Animais , Óvulo , Pisos e Cobertura de Pisos , Criação de Animais Domésticos , Bem-Estar do Animal
13.
J Exp Psychol Learn Mem Cogn ; 49(12): 2003-2033, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38127499

RESUMO

Typing slows at the middle of the word. The exact nature of the slowdown is still disputed. Research on attentional and motoric effects in typing suggests that the slowdown is purely a function of chunking of letters in creating the motor output; this approach posits no further influence of linguistic information during output. Research from a psycholinguistic perspective does posit lexical and sublexical effects during output and explains the midword slowing as a function of slowdowns at the boundaries of sublexical units. Across four experiments, using three different typing tasks, we investigated the typing of compound (schoolteacher) and pseudocompound (carpet) words. Typing at the midword region is sensitive to the morphological structure of the word and to linguistic properties of the word and its (pseudo)constituents (e.g., linguistic information about school and teacher affects schoolteacher, and car and pet affects carpet). These findings suggest that typing compounds involves a hierarchical plan consisting of two separate motor plans for each constituent executed sequentially such that the output of letters is sensitive to the number of letters within that plan, the position of the sequence in the hierarchy (e.g., first vs. second constituent), and the morphemic structure of the to-be-typed word. Surprisingly, given that pseudocompound lexical representations should not include the pseudoconstituents and given that our tasks in the first three experiments demand full access to the lexical representation before typing, pseudocompound typing is also sensitive to the pseudoconstituent characteristics, suggesting that, during typing, the system attempts to build a compound-like structure. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Assuntos
Pisos e Cobertura de Pisos , Reconhecimento Visual de Modelos , Humanos , Psicolinguística , Linguística , Memória
14.
Eur J Med Res ; 28(1): 530, 2023 Nov 16.
Artigo em Inglês | MEDLINE | ID: mdl-37974270

RESUMO

BACKGROUND: Gait impairment is common in Parkinson's disease (PD) patients, which greatly reduces their quality of life. Executive dysfunction is associated with gait impairment. Compensatory strategies, including visual cues, have been shown to be effective in improving PD gait. In this study, we aimed to understand whether carpets with visual cues could improve PD gait, and how the improvement varies across patients with different executive function state. METHODS: We designed carpets with chessboard and stripe cues. A total of 65 Chinese PD patients were recruited. Movement Disorder Society Unified Parkinson's Disease Rating Scale, L-dopa equivalent daily dosage, Hoehn & Yahr stage, Frontal Assessment Battery, Mini Mental State Examination Scale, Hamilton Anxiety Scale, and Hamilton Depression Scale were evaluated. Gait parameters including stride length, gait speed and fall risk were recorded by a wearable electronic device. RESULTS: The stride length and gait speed were significantly improved and the fall risk was significantly mitigated when PD patients walked on carpets with chessboard and stripe patterns. Further analysis showed the amelioration of gait parameters was independent of executive dysfunction. CONCLUSIONS: Our study demonstrates that carpets with visual cues can improve the gait of PD patients even in those with mild executive dysfunction.


Assuntos
Doença de Parkinson , Humanos , Doença de Parkinson/complicações , Função Executiva , Sinais (Psicologia) , Pisos e Cobertura de Pisos , Qualidade de Vida , Marcha
15.
Biol Lett ; 19(10): 20230344, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37817574

RESUMO

Anoxia/re-oxygenation (AR) results in elevated unchecked oxidative stress and mediates irreversible damage within the brain for most vertebrates. Succinate accumulation within mitochondria of the ischaemic brain appears to increase the production of reactive oxygen species (ROS) upon re-oxygenation. Two closely related elasmobranchs, the epaulette shark (Hemiscyllium ocellatum) and the grey carpet shark (Chiloscyllium punctatum) repeatedly experience near anoxia and re-oxygenation in their habitats and have adapted to survive AR at tropical temperatures without significant brain injuries. However, these anoxia-tolerant species display contrasting strategies to survive AR, with only H. ocellatum having the capacity to supress metabolism and H. ocellatum mitochondria the capacity to depress succinate oxidation post-AR. We measured oxygen consumption alongside ROS production mediated by elevated succinate in mitochondria of permeabilized cerebellum from both shark species. Although mitochondrial respiration remained similar for both species, the ROS production in H. ocellatum was half that of C. punctatum in phosphorylating and non-phosphorylating mitochondria. Maximum ROS production in H. ocellatum was mediated by succinate loads 10-fold higher than in C. punctatum mitochondria. The contrasting survival strategies of anoxia-tolerant sharks reveal the significance of mitigating ROS production under elevated succinate load during AR, shedding light on potential mechanisms to mitigate brain injury.


Assuntos
Tubarões , Animais , Tubarões/metabolismo , Espécies Reativas de Oxigênio/metabolismo , Ácido Succínico/metabolismo , Pisos e Cobertura de Pisos , Hipóxia/metabolismo , Oxigênio/metabolismo
16.
BMC Health Serv Res ; 23(1): 1088, 2023 Oct 11.
Artigo em Inglês | MEDLINE | ID: mdl-37821939

RESUMO

BACKGROUND: A constellation of often disabling long-term physical symptoms enduring after an acute SARS-COV-2 infection is commonly referred to as Long COVID. Since Long COVID is a new clinical entity, research is required to clarify treatment needs and experiences of individuals affected. This qualitative descriptive study aimed to provide insight into Long COVID treatment and service experiences and preferences of individuals experiencing Long COVID and the intersections with mental health. METHODS: The study was conducted out of a tertiary care mental health hospital, with online recruitment from the community across Canada. A total of 47 individuals (average age = 44.9) participated in one of 11 focus groups between June and December 2022. Five focus groups were conducted with participants who had pre-existing mental health concerns prior to contracting SARS-CoV-2, and six were with people with Long COVID but without pre-existing mental health concerns. A semi-structured interview guide asked about service experiences and service preferences, including mental health and well-being services. Discussions were recorded, transcribed, and analyzed using codebook thematic analysis. RESULTS: When accessing services for Long COVID, patients experienced: (1) systemic barriers to accessing care, and (2) challenges navigating the unknowns of Long COVID, leading to (3) negative impacts on patient emotional well-being and recovery. Participants called for improvements in Long COVID care, with a focus on: (1) developing Long COVID-specific knowledge and services, (2) enhancing support for financial well-being, daily living, and building a Long COVID community, and (3) improving awareness and the public representation of Long COVID. CONCLUSIONS: Substantial treatment barriers generate considerable burden for individuals living with Long COVID. There is a pressing need to improve treatment, social supports, and the social representation of Long COVID to create integrated, accessible, responsive, and ongoing support systems.


Assuntos
COVID-19 , Saúde Mental , Humanos , Adulto , Pessoa de Meia-Idade , Síndrome Pós-COVID-19 Aguda , COVID-19/epidemiologia , COVID-19/terapia , Pisos e Cobertura de Pisos , SARS-CoV-2 , Pesquisa Qualitativa
17.
PLoS One ; 18(10): e0292815, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37824569

RESUMO

Controlling the deformation rate is the key to improving the product quality of engineered wood flooring. In this work, the changes in the deformation rate of engineered wood flooring were in focus with cold-pressing, response surface methodology, and adaptive network-based fuzzy inference system were used to explore the relationship between deformation rate and processing parameters, including adhesive spreading rate, pressing time, and pressing pressure. According to the results, the deformation rate was positively related to pressing time, while it increased first and then decreased with both the increase of adhesive spreading rate and pressing pressure. Meanwhile, a mathematical model was developed, and the significant influence of each term on the deformation rate was analyzed. This model had high feasibility and can be used to describe the relationship between the deformation rate and processing parameters. Furthermore, an adaptive network-based fuzzy inference system model was established. It has higher accuracy than that of the response surface methodology model, and it can be used for predicting deformation rate and optimizing processing parameters. Finally, an optimal processing conditions with the lowest deformation rate was determined as follows: 147 g/m2 adhesive spreading rate, 12s pressing time, and 1.2 MPa pressing pressure, and it hope to be adopted in the industrial processing of engineered wood flooring with respective of the higher product quality and lower production costs.


Assuntos
Adesivos , Madeira , Pisos e Cobertura de Pisos , Indústrias
18.
J Am Med Dir Assoc ; 24(12): 1990-1995.e1, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37690460

RESUMO

OBJECTIVES: Residents in long-term care (LTC) are at high risk for falls, and falls in LTC often result in impact to the head, with clinical consequences that may be challenging to detect. We examined whether the survival of LTC residents associates with falls and fall-related head impacts. DESIGN: Prospective cohort study. SETTING AND PARTICIPANTS: This study was conducted in 2 Vancouver-area LTC homes where falls were captured on video from surveillance cameras. A total of 232 participants (133 females, 99 males) experienced at least 1 fall captured on video, among whom 84% (n = 194) died between January 2011 and January 2020. The mean age at death was 86.5 (SD = 8.5) years, and the mean survival time after enrollment to this study was 3.8 (SD = 2.1) years. METHODS: Univariable and multivariable models were used to determine how survival time depended on the rate of falls (falls per 365 days), the percentage of falls on video involving head impact, sex, age at death, and baseline physical and cognitive status. RESULTS: On average, participants experienced 6.2 (SD = 7.0) falls per 365 days, and 36.9% (SD = 36.3) of video-captured falls resulted in head impact. In multivariable analyses, an increase of 1 fall per 365 days resulted in a 4.2% higher risk of death [hazard ratio (HR) = 1.042, 95% CI 1.023-1.062, P < .001]. A 1% increase in falls involving head impact resulted in an 0.5% higher risk of death (HR 1.005, 95% CI 1.001-1.010, P = .015). Participants who experienced head impact in all video-captured falls had a 50% higher risk for death than those who always avoided head impact. CONCLUSIONS AND IMPLICATIONS: Survival in LTC is associated with the rate of falls and percentage of falls involving head impact. Improved efforts are required to prevent falls in LTC, and reduce the frequency and consequences of head impacts during falls (eg, through compliant flooring).


Assuntos
Pisos e Cobertura de Pisos , Assistência de Longa Duração , Masculino , Feminino , Humanos , Idoso , Assistência de Longa Duração/métodos , Estudos Prospectivos , Gravação em Vídeo
19.
Bioresour Technol ; 387: 129619, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37549715

RESUMO

The wastewater treatment efficiency of Diplosphaera mucosa VSPA was enhanced by optimising five input parameters and increasing the biomass yield. pH, temperature, light intensity, wastewater percentage (pollutant concentration), and N/P ratio were optimised, and their effects were studied. Two competitive techniques, response surface methodology (RSM) and artificial neural network (ANN), were applied for constructing predictive models using experimental data generated according to central composite design. Both MATLAB and Python were used for constructing ANN models. ANN models predicted the experimental data with high accuracy and less error than RSM models. Generated models were hybridised with a genetic algorithm (GA) to determine the optimised values of input parameters leading to high biomass productivity. ANN-GA hybridisation approach performed in Python presented optimisation results with less error (0.45%), which were 7.8 pH, 28.8 °C temperature, 105.20 µmol m-2 s-1 light intensity, 93.10 wastewater % (COD) and 23.5 N/P ratio.


Assuntos
Pisos e Cobertura de Pisos , Águas Residuárias , Indústria Têxtil , Redes Neurais de Computação , Mucosa , Algoritmos
20.
Forensic Sci Int ; 350: 111805, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37556977

RESUMO

Bloodstains are typically encountered in violent incidents involving the use of a weapon or physical actions, such as punching, kicking, or stamping. Bloodstain pattern analysis can provide inceptive evidence or intelligence about what happened in an alleged incident, the sequence of events, along with indicating possible suspects if blood is analysed through DNA profiling. This research project focused on the differences in patterns created on footwear during a violent action, such as stamping on a person, and a non-violent action, such as walking through a pool of blood. In this project, several experiments were designed to simulate the stamping and walking actions on a surface wet with blood: carpet, lino flooring, and belly pork meat. Two volunteers with varying body weights were recruited to perform the two actions, using a pair of trainers and a pair of Wellington boots. Defibrinated horse blood was used to simulate real human blood. It was found that the patterns created from stamping and walking through blood differed by the type of pattern and the number and size of stains. The footwear used in the stamping action was characterised by a larger contact stain on the sole than those used in the walking actions: ∼209 mm in length by ∼92 mm in width versus ∼65 mm in length by ∼60 mm in width. The stamping action produced a large number of impact spatters (∼435) on the sides of the footwear versus no impact spatters in the walking actions. The presence of impact spatters was found to be the most prominent feature that differentiated between the two actions. The findings were statistically significant (p < 0.05) and could assist in evaluating whether a defendant was actively involved in a stamping action, or the evidence found was due to innocent reasons.


Assuntos
Manchas de Sangue , Humanos , Animais , Cavalos , Caminhada , Impressões Digitais de DNA , Pisos e Cobertura de Pisos
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